Across TCGA patient cohorts, C7orf61 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C7orf61-associated genes across cancer lineages are eIF4E, Rab11, and EGFR_pY1068. Each is linked with C7orf61 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf61-to-partner and partner-to-C7orf61 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf61→partner) and Y-score (partner→C7orf61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.231	+3.169	.045	.020	3	1
UCEC	Rab11 →	-0.168	-3.169	.034	.020	3	1
UCEC	EGFR_pY1068 →	-0.282	-3.169	.040	.020	2	1
UCEC	Tuberin →	+0.417	+3.169	.004	.020	2	1
UCEC	CD49b →	-0.467	-3.156	.002	.020	2	1
UCEC	p62 Lck ligand →	+0.632	+3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

C7orf61 survival (RNA) · tumor vs normal (RNA) · all C7orf61 data types