Across TCGA pan-cancer cohorts, C7orf61 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated C7orf61 data layer compared with 2 for mutation status.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C7orf61 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C7orf61 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THCA show a favorable association.
KIRC, UCEC, and SKCM are the cancer types where C7orf61 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.