C7orf50

Across TCGA pan-cancer cohorts, C7orf50 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated C7orf50 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C7orf50 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C7orf50 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

HNSC, UCEC, and LUAD are the cancer types where C7orf50 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.706	0.930	.009	28	view →
UCEC	DFS	Median	II,III,IV	0.936	0.456	.003	14	view →
LUAD	DFS	Median	All	0.514	0.736	.021	13	view →
GBM	OS	Median	All	0.625	0.439	.014	2	view →
LSCC	DFS	Tertile	III,IV	0.865	0.514	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

C7orf50–HNSC (OS)

Open the HNSC breakdown →