C7orf50

Across TCGA patient cohorts, C7orf50 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C7orf50-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, tRNA thio-modification, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with C7orf50 in more than 22 cancer types. Because this analysis shows association rather than direction, both C7orf50-to-partner and partner-to-C7orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by C7orf50-low versus C7orf50-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf50→partner) and Y-score (partner→C7orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.063	+0.756	<.001	<.001	3	23
READ	tRNA thio-modification →	+0.052	+0.399	<.001	.002	2	23
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	-0.074	-0.741	<.001	<.001	3	21
DLBC	Negative regulation of hematopoietic stem cell differentiation →	-0.070	-0.848	.009	.009	1	22
ESCA	Regulation of Golgi organization →	-0.051	-0.553	<.001	<.001	3	20
DLBC	Positive regulation of MHC class II biosynthetic process →	-0.106	-0.972	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

[4Fe-4S] cluster assembly by C7orf50 expression — DLBC

Explore this box plot interactively →