C7orf50

Across TCGA cell cohorts, C7orf50 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,969 significant associations in total. CNS shows the largest number of these associations.

The most reproducible C7orf50-associated GO terms across cancer lineages are Maintenance of unfolded protein, Meiotic mismatch repair, and Activation of protein kinase A activity. Each is linked with C7orf50 in more than 13 cancer types. Because this analysis shows association rather than direction, both C7orf50-to-partner and partner-to-C7orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of unfolded protein grouped by C7orf50-low versus C7orf50-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf50→partner) and Y-score (partner→C7orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maintenance of unfolded protein →	+0.102	+0.745	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Meiotic mismatch repair →	+0.128	+1.419	<.001	<.001	3	13
OVARY	Activation of protein kinase A activity →	+0.165	+0.948	<.001	<.001	3	11
LARGE_INTESTINE	Meiotic telomere tethering at nuclear periphery →	+0.113	+0.821	<.001	<.001	3	10
LARGE_INTESTINE	Meiotic telomere clustering →	+0.113	+0.821	<.001	<.001	3	10
BLOOD_Myeloma	Regulation of isotype switching to IgG isotypes →	+0.112	+1.256	.001	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

Maintenance of unfolded protein by C7orf50 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →