C7orf50

Across TCGA cell cohorts, C7orf50 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C7orf50-associated genes across cancer lineages are KRT85, OR4F4, and KRT73. Each is linked with C7orf50 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf50-to-partner and partner-to-C7orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT85 grouped by C7orf50-low versus C7orf50-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf50→partner) and Y-score (partner→C7orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KRT85 →	+0.448	+4.145	<.001	.001	3	1
LARGE_INTESTINE	OR4F4 →	+0.014	+3.688	.001	.002	3	1
LARGE_INTESTINE	KRT73 →	+0.057	+3.196	.007	.007	3	1
LARGE_INTESTINE	ADAMTS4 →	+0.148	+3.626	<.001	.006	2	1
LARGE_INTESTINE	FCGR2B →	+0.118	+3.453	.005	.009	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

KRT85 by C7orf50 expression — LARGE_INTESTINE

Explore this box plot interactively →