C7orf33

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C7orf33 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C7orf33 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher C7orf33 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C7orf33 expression acts as an unfavorable survival marker.

THCA and LUAD are the cancer types where C7orf33 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSMedianAll0.2940.945<.0018view →
LUADOSMedianIII,IV0.0680.680<.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C7orf33–THCA (OS)

Kaplan–Meier survival curve for C7orf33 mutant vs wild-type samples in THCA.

Open the THCA breakdown →

Exploration