C7orf33

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, C7orf33 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C7orf33’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where C7orf33 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C7orf33 is over-expressed in tumor.

LUSC, KIRC, and BRCA are the cancer types where C7orf33 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C7orf33 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCAllAll+0.088<.0015view →
KIRCAllAll+0.027<.0015view →
BRCAAllAll+0.065.0174view →
COADAllII,III,IV+0.033.0482view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

C7orf33–LUSC

Tumor-vs-normal expression box plot for C7orf33 RNA in LUSC.

Open the LUSC breakdown →

Exploration