C7orf33

Across TCGA patient cohorts, C7orf33 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,267 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible C7orf33-associated GO terms across cancer lineages are Positive regulation of protein ubiquitination, DTTP metabolic process, and Nucleoside triphosphate metabolic process. Each is linked with C7orf33 in more than 9 cancer types. Because this analysis shows association rather than direction, both C7orf33-to-partner and partner-to-C7orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein ubiquitination grouped by C7orf33-low versus C7orf33-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf33→partner) and Y-score (partner→C7orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of protein ubiquitination →	+0.054	+0.077	<.001	.001	3	10
STAD	DTTP metabolic process →	+0.046	+0.098	<.001	<.001	3	10
STAD	Nucleoside triphosphate metabolic process →	+0.067	+0.107	<.001	.002	3	10
STAD	DNA replication initiation →	+0.084	+0.145	<.001	<.001	3	9
STAD	Deoxyribonucleotide biosynthetic process →	+0.058	+0.088	<.001	<.001	3	9
STAD	Response to heat →	+0.057	+0.113	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,267 associations by consensus.

Positive regulation of protein ubiquitination by C7orf33 expression — STAD

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