C7orf33

Across TCGA cell cohorts, C7orf33 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C7orf33-associated genes across cancer lineages are CCL18, LCE1C, and SLC5A8. Each is linked with C7orf33 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf33-to-partner and partner-to-C7orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by C7orf33-low versus C7orf33-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf33→partner) and Y-score (partner→C7orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCL18 →	+0.129	+5.415	<.001	.004	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KLF18 →	+0.006	+5.201	.003	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.395	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CCL18 by C7orf33 expression — LARGE_INTESTINE

Explore this box plot interactively →