C7orf31

Across TCGA cell cohorts, C7orf31 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,958 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C7orf31-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Golgi vesicle transport, and Regulation of postsynaptic membrane potential. Each is linked with C7orf31 in more than 11 cancer types. Because this analysis shows association rather than direction, both C7orf31-to-partner and partner-to-C7orf31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by C7orf31-low versus C7orf31-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf31→partner) and Y-score (partner→C7orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of myoblast fusion →	+0.100	+1.162	<.001	<.001	3	12
OESOPHAGUS	Golgi vesicle transport →	+0.073	+1.089	.003	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Regulation of postsynaptic membrane potential →	-0.146	-0.637	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.081	+0.831	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.054	+0.694	.001	.002	3	10
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+0.884	.002	.009	1	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,958 associations by consensus.

Negative regulation of myoblast fusion by C7orf31 expression — SOFT_TISSUE

Explore this box plot interactively →