C7orf31

Across TCGA cell cohorts, C7orf31 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C7orf31-associated genes across cancer lineages are CDCP2, SAMD7, and DPPA5. Each is linked with C7orf31 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf31-to-partner and partner-to-C7orf31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCP2 grouped by C7orf31-low versus C7orf31-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf31→partner) and Y-score (partner→C7orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CDCP2 →	+0.024	+4.347	<.001	.001	3	1
LUNG_NSCLC_LUAD	SAMD7 →	+0.053	+4.481	<.001	.001	3	1
LUNG_NSCLC_LUAD	DPPA5 →	+0.068	+3.544	<.001	.009	3	1
BLOOD_Leukemia	SLC5A7 →	+0.006	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CDCP2 by C7orf31 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →