C7orf26

Across TCGA pan-cancer cohorts, C7orf26 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated C7orf26 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher C7orf26 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C7orf26 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where C7orf26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	III,IV	0.579	0.214	.003	20	view →
HNSC	DFS	Quartile	III,IV	0.554	0.907	.008	14	view →
CCRCC	DFS	Quartile	II,III,IV	0.749	1.000	.017	10	view →
LSCC	DFS	Median	All	0.975	0.895	.032	4	view →
LUAD	DFS	Median	All	0.690	0.910	.040	2	view →
GBM	OS	Tertile	All	0.694	0.888	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

C7orf26–PDAC (DFS)

Open the PDAC breakdown →