C7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C7 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C7-associated proteins across cancer lineages are KANK2, LTBP2, and LUM. Each is linked with C7 in more than 9 cancer types. Because this analysis shows association rather than direction, both C7-to-partner and partner-to-C7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C7 versus KANK2 in UCEC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C7→partner) and Y-score (partner→C7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKANK2 →+0.847+2.384<.001<.001310
CCRCCLTBP2 →+1.177+2.153<.001<.001310
GBMLUM →+1.051+1.571<.001<.001310
HNSCSYNPO2 →+1.085+1.115<.001<.001310
UCECSYNPO2_S264 →+1.363+2.916<.001<.001310
CCRCCSYNPO2_S363 →+1.389+2.941<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 26,450 associations by consensus.

C7 vs KANK2 — UCEC

Per-sample scatter of C7 vs KANK2 in UCEC (Pearson r = 0.67).

Explore this scatter interactively →

Exploration