C6orf62

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C6orf62 mutation is significantly associated with the RNA expression of many other genes, with 2,052 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf62-associated genes across cancer lineages are TRDV2, PGBD4P2, and RNU6-386P. Each is linked with C6orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf62-to-partner and partner-to-C6orf62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDV2 grouped by C6orf62-low versus C6orf62-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf62→partner) and Y-score (partner→C6orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCATRDV2 →+0.117+3.758.003.00832
READPGBD4P2 →+0.162+6.257<.001.00131
HNSCRNU6-386P →+0.268+7.954<.001.00831
UCECYTHDF3-AS1 →+0.731+2.617<.001.00531
UCECGPR75-ASB3 →+0.073+2.380<.001.00531
UCECBNIP3P4 →+0.051+2.577<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,052 associations by consensus.

TRDV2 by C6orf62 expression — BLCA

Box plot of TRDV2 in C6orf62-low vs C6orf62-high samples in BLCA.

Explore this box plot interactively →

Exploration