C6orf62

Across TCGA pan-cancer cohorts, C6orf62 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of C6orf62’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where C6orf62 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C6orf62 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

HNSC, LIHC, and KIRC are the cancer types where C6orf62 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C6orf62 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.660	<.001	12	view →
LIHC	Female	II,III,IV	+1.149	<.001	9	view →
KIRC	All	All	+0.370	<.001	9	view →
KICH	Female	II,III,IV	−1.302	<.001	8	view →
BRCA	All	II,III,IV	+0.436	<.001	8	view →
STAD	All	II,III,IV	+0.817	<.001	7	view →
KIRP	Female	II,III,IV	+0.791	.011	6	view →
BLCA	All	All	+0.671	<.001	6	view →
CHOL	Male	All	+2.243	<.001	5	view →
LUSC	Male	All	−0.329	.004	3	view →
ESCA	All	All	+0.593	.004	2	view →
COAD	Male	All	+0.347	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

C6orf62–HNSC

Open the HNSC breakdown →