C6orf62

Across TCGA patient cohorts, C6orf62 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf62-associated genes across cancer lineages are EGFR_pY1068, eIF4G, and FOXO3a_pS318_S321. Each is linked with C6orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf62-to-partner and partner-to-C6orf62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by C6orf62-low versus C6orf62-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf62→partner) and Y-score (partner→C6orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.234	-2.906	.028	.001	3	1
UCEC	eIF4G →	+0.319	+2.321	.015	.034	3	1
UCEC	FOXO3a_pS318_S321 →	-0.113	-2.449	.032	.019	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.568	+2.906	.008	.001	3	1
UCEC	INPP4B →	-0.303	-3.321	.027	.009	3	1
UCEC	JNK_pT183_Y185 →	-0.231	-3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

EGFR_pY1068 by C6orf62 expression — UCEC

Explore this box plot interactively →