C6orf52

Across TCGA cell cohorts, C6orf52 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,094 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C6orf52-associated GO terms across cancer lineages are Cardiac muscle cell action potential involved in contraction, Regulation of response to type II interferon, and Regulation of type II interferon-mediated signaling pathway. Each is linked with C6orf52 in more than 6 cancer types. Because this analysis shows association rather than direction, both C6orf52-to-partner and partner-to-C6orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell action potential involved in contraction grouped by C6orf52-low versus C6orf52-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf52→partner) and Y-score (partner→C6orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cardiac muscle cell action potential involved in contraction →	-0.099	-1.449	.002	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of response to type II interferon →	-0.112	-0.603	.007	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of type II interferon-mediated signaling pathway →	-0.112	-0.603	.007	.001	3	6
BLOOD_Myeloma	Cellular pigmentation →	+0.043	+1.077	.006	.007	3	5
BLOOD_Myeloma	Multivesicular body organization →	+0.052	+1.381	.001	.005	3	5
BLOOD_Myeloma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.055	+1.260	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,094 associations by consensus.

Cardiac muscle cell action potential involved in contraction by C6orf52 expression — BLOOD_Myeloma

Explore this box plot interactively →