Across TCGA patient cohorts, C6orf47 mutation is significantly associated with the RNA expression of many other genes, with 447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf47-associated genes across cancer lineages are COX5BP1, RNA5SP121, and MTND2P17. Each is linked with C6orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf47-to-partner and partner-to-C6orf47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf47→partner) and Y-score (partner→C6orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	COX5BP1 →	+0.094	+5.770	<.001	.003	3	1
KIRP	RNA5SP121 →	+0.668	+5.376	<.001	.005	3	1
KIRP	MTND2P17 →	+0.064	+5.628	<.001	.004	3	1
BLCA	OR8B4 →	+0.054	+7.640	<.001	.009	3	1
UCEC	RPS10-NUDT3 →	+0.255	+3.724	.008	.002	3	1
UCEC	RPL23AP88 →	+0.214	+2.332	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

Exploration

C6orf47 survival (RNA) · tumor vs normal (RNA) · all C6orf47 data types