C6orf223

Across TCGA patient cohorts, C6orf223 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,709 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C6orf223-associated proteins across cancer lineages are ECT2_T359, IDI1, and XRCC6_T455. Each is linked with C6orf223 in more than 4 cancer types. Because this analysis shows association rather than direction, both C6orf223-to-partner and partner-to-C6orf223 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C6orf223 versus ECT2_T359 in LUAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf223→partner) and Y-score (partner→C6orf223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ECT2_T359 →	+1.187	+1.182	<.001	<.001	3	5
COAD	IDI1 →	+0.533	+0.921	.007	.004	3	5
OV	XRCC6_T455 →	+0.751	+0.881	<.001	.003	3	5
OV	TOPBP1 →	+0.348	+0.997	.003	.001	3	5
CCRCC	FLT1 →	+0.773	+1.460	<.001	<.001	3	5
OV	FEN1 →	+0.463	+0.877	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,709 associations by consensus.

C6orf223 vs ECT2_T359 — LUAD

Explore this scatter interactively →