Across TCGA pan-cancer cohorts, C6orf136 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C6orf136 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher C6orf136 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated C6orf136 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where C6orf136 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	1.000	0.816	.005	13	view →
PDAC	DFS	Median	All	0.568	0.904	.009	12	view →
HNSC	DFS	Median	II,III,IV	0.921	0.593	.048	2	view →
LUAD	OS	Median	All	1.000	0.735	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: C6orf136 tumor-vs-normal RNA expression · all C6orf136 data types