C6orf118

Across TCGA cell cohorts, C6orf118 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C6orf118-associated genes across cancer lineages are KRTAP12-1, KIR2DS4, and OR13H1. Each is linked with C6orf118 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf118-to-partner and partner-to-C6orf118 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP12-1 grouped by C6orf118-low versus C6orf118-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf118→partner) and Y-score (partner→C6orf118) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRTAP12-1 →	+0.066	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KIR2DS4 →	+0.023	+4.807	<.001	.006	3	1
LUNG_SCLC	OR13H1 →	+0.065	+3.602	<.001	.005	3	1
LUNG_SCLC	OR14I1 →	+0.117	+3.070	<.001	.009	3	1
LUNG_SCLC	CCL4 →	+0.044	+3.906	.001	.002	3	1
LUNG_SCLC	NXPE1 →	+0.008	+3.256	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

KRTAP12-1 by C6orf118 expression — BLOOD_Myeloma

Explore this box plot interactively →