C5orf66-AS2

Across TCGA patient cohorts, C5orf66-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,126 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C5orf66-AS2-associated proteins across cancer lineages are ARHGAP31, TRAPPC11_S71, and PPL. Each is linked with C5orf66-AS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both C5orf66-AS2-to-partner and partner-to-C5orf66-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf66-AS2 versus ARHGAP31 in OV, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf66-AS2→partner) and Y-score (partner→C5orf66-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARHGAP31 →	-0.666	-0.023	<.001	.005	3	4
CCRCC	TRAPPC11_S71 →	-0.592	-0.502	.007	.009	3	4
LSCC	PPL →	+0.598	+0.959	<.001	<.001	3	4
HNSC	SRFBP1_S203 →	+0.689	+0.590	<.001	<.001	3	4
LSCC	TNS3_S1149 →	-0.567	-0.670	.001	.002	3	4
CCRCC	HEATR1 →	+0.226	+0.440	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,126 associations by consensus.

C5orf66-AS2 vs ARHGAP31 — OV

Explore this scatter interactively →