C5orf66-AS2

Across TCGA patient cohorts, C5orf66-AS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,153 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C5orf66-AS2-associated GO terms across cancer lineages are Signal transduction by p53 class mediator, Response to estradiol, and Positive regulation of intracellular transport. Each is linked with C5orf66-AS2 in more than 12 cancer types. Because this analysis shows association rather than direction, both C5orf66-AS2-to-partner and partner-to-C5orf66-AS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction by p53 class mediator grouped by C5orf66-AS2-low versus C5orf66-AS2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf66-AS2→partner) and Y-score (partner→C5orf66-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Signal transduction by p53 class mediator →	+0.036	+0.043	<.001	<.001	3	13
STAD	Response to estradiol →	+0.032	+0.048	<.001	<.001	3	12
STAD	Positive regulation of intracellular transport →	+0.037	+0.045	<.001	<.001	3	12
STAD	Positive regulation of intracellular protein transport →	+0.041	+0.042	<.001	<.001	3	12
STAD	Obsolete ncRNA transcription →	+0.036	+0.045	<.001	<.001	3	11
STAD	Regulation of double-strand break repair →	+0.033	+0.050	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,153 associations by consensus.

Signal transduction by p53 class mediator by C5orf66-AS2 expression — STAD

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