C5orf58

Across TCGA patient cohorts, C5orf58 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,468 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C5orf58-associated proteins across cancer lineages are SAMSN1_S23, STK10, and CYBB. Each is linked with C5orf58 in more than 9 cancer types. Because this analysis shows association rather than direction, both C5orf58-to-partner and partner-to-C5orf58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf58 versus SAMSN1_S23 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf58→partner) and Y-score (partner→C5orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAMSN1_S23 →	+0.928	+0.512	<.001	<.001	3	10
LSCC	STK10 →	+0.421	+0.575	<.001	<.001	3	10
LSCC	CYBB →	+0.735	+0.600	<.001	<.001	3	10
GBM	DEF6 →	+0.701	+0.645	<.001	<.001	3	10
GBM	DOCK2 →	+0.741	+0.676	<.001	<.001	3	10
GBM	FMNL1 →	+0.703	+0.677	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,468 associations by consensus.

C5orf58 vs SAMSN1_S23 — GBM

Explore this scatter interactively →