Across TCGA patient cohorts, C5orf52 mutation is significantly associated with the RNA expression of many other genes, with 614 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf52-associated genes across cancer lineages are PINCR, RNU6-502P, and TRDJ2. Each is linked with C5orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf52-to-partner and partner-to-C5orf52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf52→partner) and Y-score (partner→C5orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PINCR →	+0.397	+2.355	<.001	.002	3	2
COAD	RNU6-502P →	+0.410	+4.392	<.001	.006	3	1
COAD	TRDJ2 →	+0.709	+3.799	.006	.002	3	1
COAD	LINC02663 →	+0.202	+3.636	.008	.006	3	1
COAD	LNCAROD →	+0.846	+3.847	.001	.005	3	1
COAD	UBE2V1P16 →	+0.164	+5.409	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 614 associations by consensus.

Exploration

C5orf52 survival (RNA) · tumor vs normal (RNA) · all C5orf52 data types