Across TCGA patient cohorts, C5orf49 protein abundance is significantly associated with the RNA expression of many other genes, with 393 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C5orf49-associated genes across cancer lineages are ZNF415, MFNG, and VNN1. Each is linked with C5orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf49-to-partner and partner-to-C5orf49 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf49→partner) and Y-score (partner→C5orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF415 →	+1.077	+0.577	<.001	.003	3	2
LSCC	MFNG →	+0.710	+0.608	.008	.009	3	1
LSCC	VNN1 →	+0.931	+0.959	.001	.001	3	1
LSCC	GRIN3B →	+0.882	+0.726	<.001	<.001	3	1
LSCC	CFAP58 →	+0.643	+0.606	.004	.009	3	1
LSCC	NXF5 →	+0.076	+1.046	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 393 associations by consensus.

Exploration

C5orf49 survival (RNA) · tumor vs normal (RNA) · all C5orf49 data types