Across TCGA patient cohorts, C5orf49 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf49-associated genes across cancer lineages are HESX1, KIR3DL1, and DNAJC7. Each is linked with C5orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf49-to-partner and partner-to-C5orf49 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf49→partner) and Y-score (partner→C5orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HESX1 →	+0.672	+3.223	.001	.009	3	1
UCEC	KIR3DL1 →	+0.255	+2.910	.002	.004	3	1
UCEC	DNAJC7 →	+0.705	+3.210	<.001	.009	3	1
UCEC	TIMM22 →	+0.527	+3.223	.002	.009	3	1
LUAD	OR5L2 →	+0.034	+7.930	<.001	.008	3	1
LUAD	AARS1P1 →	+0.069	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration

C5orf49 survival (RNA) · tumor vs normal (RNA) · all C5orf49 data types