Across TCGA cell cohorts, C5orf49 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C5orf49-associated genes across cancer lineages are OBP2A, NPY, and CPB1. Each is linked with C5orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf49-to-partner and partner-to-C5orf49 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf49→partner) and Y-score (partner→C5orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OBP2A →	+0.073	+2.878	.006	.009	3	1
LARGE_INTESTINE	NPY →	+0.064	+3.722	<.001	.002	3	1
LARGE_INTESTINE	CPB1 →	+0.034	+3.103	.007	.004	3	1
LARGE_INTESTINE	KRT6C →	+0.939	+3.334	<.001	.008	3	1
LARGE_INTESTINE	ENTHD1 →	+0.026	+3.554	.002	.002	3	1
LARGE_INTESTINE	FBXO39 →	+0.139	+2.906	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

C5orf49 survival (RNA) · tumor vs normal (RNA) · all C5orf49 data types