Across TCGA pan-cancer cohorts, C5orf47 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C5orf47 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher C5orf47 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C5orf47 expression acts as an unfavorable survival marker.

DLBC and UCEC are the cancer types where C5orf47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	II,III,IV	0.118	0.802	.025	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: C5orf47 tumor-vs-normal RNA expression · all C5orf47 data types