Across TCGA patient cohorts, C5orf47 mutation is significantly associated with the RNA expression of many other genes, with 565 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf47-associated genes across cancer lineages are CENPU, GBP5, and ZC3H18. Each is linked with C5orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf47-to-partner and partner-to-C5orf47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf47→partner) and Y-score (partner→C5orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+1.008	+3.491	<.001	.002	3	1
UCEC	GBP5 →	+1.360	+3.470	<.001	.003	3	1
UCEC	ZC3H18 →	+0.765	+3.491	<.001	.002	3	1
UCEC	THEM4 →	-1.146	-3.405	<.001	.005	3	1
UCEC	CALM3 →	+0.666	+3.480	.001	.002	3	1
UCEC	CLDND2 →	+0.777	+3.209	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 565 associations by consensus.

Exploration

C5orf47 survival (RNA) · tumor vs normal (RNA) · all C5orf47 data types