C5orf46

Across TCGA patient cohorts, C5orf46 RNA expression is significantly associated with the RNA expression of many other genes, with 10,264 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible C5orf46-associated genes across cancer lineages are SERPINE1, COL1A1, and COL10A1. Each is linked with C5orf46 in more than 27 cancer types. Because this analysis shows association rather than direction, both C5orf46-to-partner and partner-to-C5orf46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf46 versus SERPINE1 in CHOL, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf46→partner) and Y-score (partner→C5orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	SERPINE1 →	+2.267	+2.291	<.001	<.001	3	28
BLCA	COL1A1 →	+2.511	+1.519	<.001	<.001	3	28
BLCA	COL10A1 →	+2.879	+1.662	<.001	<.001	3	28
BLCA	COL5A1 →	+2.202	+1.418	<.001	<.001	3	28
DLBC	THBS2 →	+2.929	+1.820	<.001	<.001	3	27
OV	LINC01614 →	+2.590	+1.451	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,264 associations by consensus.

C5orf46 vs SERPINE1 — CHOL

Explore this scatter interactively →