C5orf46

Across TCGA patient cohorts, C5orf46 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,886 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C5orf46-associated proteins across cancer lineages are THBS1, SFRP2, and FN1. Each is linked with C5orf46 in more than 8 cancer types. Because this analysis shows association rather than direction, both C5orf46-to-partner and partner-to-C5orf46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf46 versus THBS1 in COAD, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf46→partner) and Y-score (partner→C5orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	THBS1 →	+1.244	+1.664	<.001	<.001	3	9
COAD	SFRP2 →	+1.823	+1.761	<.001	<.001	3	8
OV	FN1 →	+1.245	+1.740	<.001	<.001	3	8
PDAC	LOXL2 →	+1.058	+1.591	<.001	<.001	3	8
GBM	RCN3 →	+0.697	+1.032	<.001	<.001	3	8
OV	TAGLN →	+1.212	+1.965	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,886 associations by consensus.

C5orf46 vs THBS1 — COAD

Explore this scatter interactively →