Across TCGA patient cohorts, C5orf38 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,838 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C5orf38-associated proteins across cancer lineages are IRX2_S186, IRX2_S317, and PDCD6. Each is linked with C5orf38 in more than 5 cancer types. Because this analysis shows association rather than direction, both C5orf38-to-partner and partner-to-C5orf38 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf38→partner) and Y-score (partner→C5orf38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IRX2_S186 →	+2.441	+1.914	<.001	<.001	3	6
LUAD	IRX2_S317 →	+1.173	+1.560	<.001	<.001	3	4
LSCC	PDCD6 →	+0.269	+0.546	<.001	<.001	3	3
LSCC	RICTOR →	+0.160	+0.603	<.001	<.001	3	3
LUAD	SLC16A1_S467 →	-0.903	-0.944	.004	.005	3	3
LSCC	CCDC127 →	+0.277	+0.690	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,838 associations by consensus.

Exploration

C5orf38 survival (RNA) · tumor vs normal (RNA) · all C5orf38 data types