Across TCGA cell cohorts, C5orf38 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C5orf38-associated genes across cancer lineages are GUCA1C, CBLL2, and OR10S1. Each is linked with C5orf38 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf38-to-partner and partner-to-C5orf38 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf38→partner) and Y-score (partner→C5orf38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GUCA1C →	+0.039	+5.969	<.001	.001	3	1
SKIN	CBLL2 →	+0.012	+4.415	<.001	.007	3	1
SKIN	OR10S1 →	+0.099	+4.415	<.001	.007	3	1
SKIN	SLC13A2 →	+0.015	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C5orf38 survival (RNA) · tumor vs normal (RNA) · all C5orf38 data types