C5orf34

Across TCGA patient cohorts, C5orf34 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,856 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C5orf34-associated proteins across cancer lineages are TRIP13, CDC20_T70, and CDK1. Each is linked with C5orf34 in more than 9 cancer types. Because this analysis shows association rather than direction, both C5orf34-to-partner and partner-to-C5orf34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf34 versus TRIP13 in LUAD, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf34→partner) and Y-score (partner→C5orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRIP13 →	+0.836	+0.668	<.001	<.001	3	10
OV	CDC20_T70 →	+1.363	+0.751	<.001	<.001	3	9
UCEC	CDK1 →	+0.822	+0.647	<.001	<.001	3	9
LUAD	TOP2A →	+0.928	+0.610	<.001	<.001	3	9
BRCA	TOP2A_S1106 →	+1.178	+0.516	<.001	<.001	3	9
GBM	MCM2 →	+0.975	+0.689	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,856 associations by consensus.

C5orf34 vs TRIP13 — LUAD

Explore this scatter interactively →