C5orf34-AS1

Across TCGA pan-cancer cohorts, C5orf34-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated C5orf34-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C5orf34-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C5orf34-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and PAAD show a favorable association.

KIRC, COAD, and THCA are the cancer types where C5orf34-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	IV	0.479	0.745	<.001	116	view →
COAD	DFS	Tertile	II,III,IV	0.708	0.857	<.001	77	view →
THCA	OS	Quartile	III,IV	0.366	0.931	<.001	58	view →
UVM	DFS	Median	II,III,IV	0.612	0.862	.007	48	view →
LUSC	OS	Tertile	II,III,IV	0.513	0.308	.001	48	view →
LAML	DFS	Tertile	All	0.221	0.542	.003	38	view →
PAAD	OS	Median	All	0.680	0.493	.013	24	view →
READ	OS	Tertile	III,IV	0.920	0.676	.022	22	view →
LGG	DFS	Tertile	All	0.646	0.818	<.001	20	view →
LIHC	DFS	Median	All	0.487	0.607	.016	13	view →
MESO	DFS	Tertile	II,III,IV	0.339	0.813	.019	12	view →
SKCM	OS	Median	IV	0.868	0.254	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

C5orf34-AS1–KIRC (DFS)

Open the KIRC breakdown →