C5orf17

Across TCGA patient cohorts, C5orf17 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf17-associated genes across cancer lineages are RNU6-271P, RNU2-38P, and MTND4P30. Each is linked with C5orf17 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf17-to-partner and partner-to-C5orf17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by C5orf17-low versus C5orf17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf17→partner) and Y-score (partner→C5orf17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.431	+4.267	<.001	.009	3	1
UCEC	RNU2-38P →	+0.712	+4.430	<.001	.002	3	1
UCEC	MTND4P30 →	+0.258	+4.095	.001	.005	3	1
UCEC	EIF3JP1 →	+0.564	+3.690	<.001	.009	3	1
UCEC	DEFA10P →	+0.128	+4.641	<.001	.006	3	1
UCEC	IGKV1-37 →	+0.250	+3.903	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

RNU6-271P by C5orf17 expression — UCEC

Explore this box plot interactively →