C5orf15

Across TCGA patient cohorts, C5orf15 mutation is significantly associated with the RNA expression of many other genes, with 906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf15-associated genes across cancer lineages are RNU6-1318P, RNU4-58P, and SDR42E1P4. Each is linked with C5orf15 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf15-to-partner and partner-to-C5orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by C5orf15-low versus C5orf15-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf15→partner) and Y-score (partner→C5orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1318P →	+0.256	+4.588	.002	.008	3	2
UCEC	RNU4-58P →	+0.359	+3.548	<.001	<.001	3	2
BLCA	SDR42E1P4 →	+0.111	+6.040	<.001	.001	3	2
UCEC	LIN7C →	+0.565	+2.593	.009	.006	3	1
UCEC	CPSF7 →	+0.398	+3.337	.008	.005	3	1
UCEC	DSN1 →	+0.585	+2.721	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 906 associations by consensus.

RNU6-1318P by C5orf15 expression — BLCA

Explore this box plot interactively →