C5orf15

Across TCGA cell cohorts, C5orf15 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C5orf15-associated genes across cancer lineages are CCR8, FAM205C, and ITGAD. Each is linked with C5orf15 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf15-to-partner and partner-to-C5orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCR8 grouped by C5orf15-low versus C5orf15-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf15→partner) and Y-score (partner→C5orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	FAM205C →	+0.070	+4.930	<.001	.008	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	KRT25 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KIAA1210 →	+0.010	+4.467	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CCR8 by C5orf15 expression — SOFT_TISSUE

Explore this box plot interactively →