Across TCGA patient cohorts, C5AR1 mutation is significantly associated with the RNA expression of many other genes, with 1,118 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C5AR1-associated genes across cancer lineages are UBTFL2, RNA5SP412, and LINC01997. Each is linked with C5AR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both C5AR1-to-partner and partner-to-C5AR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5AR1→partner) and Y-score (partner→C5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	UBTFL2 →	+0.069	+4.484	.006	.002	3	3
UCEC	RNA5SP412 →	+0.605	+2.967	.004	.002	3	2
BLCA	LINC01997 →	+0.112	+4.038	<.001	.002	3	2
CESC	H3P18 →	+1.511	+4.539	<.001	.008	3	2
CESC	MIR4510 →	+0.300	+5.342	<.001	.002	3	2
SKCM	SNHG30 →	+0.443	+2.189	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,118 associations by consensus.

Exploration

C5AR1 survival (RNA) · tumor vs normal (RNA) · all C5AR1 data types