C4orf51

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C4orf51 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C4orf51-associated genes across cancer lineages are PRAMEF7. Each is linked with C4orf51 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf51-to-partner and partner-to-C4orf51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF7 grouped by C4orf51-low versus C4orf51-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf51→partner) and Y-score (partner→C4orf51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPRAMEF7 →+0.022+5.539<.001.00331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PRAMEF7 by C4orf51 expression — BLOOD_Leukemia

Box plot of PRAMEF7 in C4orf51-low vs C4orf51-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration