C4orf45

Across TCGA patient cohorts, C4orf45 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,362 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C4orf45-associated proteins across cancer lineages are SFXN3, LACTB, and WDFY3. Each is linked with C4orf45 in more than 3 cancer types. Because this analysis shows association rather than direction, both C4orf45-to-partner and partner-to-C4orf45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf45 versus SFXN3 in LUAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf45→partner) and Y-score (partner→C4orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SFXN3 →	+0.400	+0.353	<.001	<.001	3	4
HNSC	LACTB →	+0.264	+0.545	.004	.004	3	4
UCEC	WDFY3 →	+0.173	+0.592	.001	.001	3	3
COAD	CALD1_S518 →	+0.493	+0.145	.005	.005	3	3
GBM	DIP2C_T264 →	+0.800	+0.461	.001	.004	3	3
LSCC	GNB4 →	+0.338	+0.461	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,362 associations by consensus.

C4orf45 vs SFXN3 — LUAD

Explore this scatter interactively →