C4orf33

Across TCGA patient cohorts, C4orf33 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,940 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf33-associated proteins across cancer lineages are TOP2A_S1247, KMT2B_S1164, and MYBBP1A. Each is linked with C4orf33 in more than 3 cancer types. Because this analysis shows association rather than direction, both C4orf33-to-partner and partner-to-C4orf33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf33 versus TOP2A_S1247 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf33→partner) and Y-score (partner→C4orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOP2A_S1247 →	-1.106	-0.649	<.001	<.001	3	4
BRCA	KMT2B_S1164 →	-1.246	-0.647	<.001	<.001	3	4
BRCA	MYBBP1A →	-0.350	-0.573	<.001	<.001	3	4
BRCA	PES1 →	-0.380	-0.762	<.001	<.001	3	4
UCEC	ADNP_S98 →	-0.811	-0.837	<.001	<.001	3	3
UCEC	ARCN1 →	+0.270	+0.962	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,940 associations by consensus.

C4orf33 vs TOP2A_S1247 — UCEC

Explore this scatter interactively →