C4orf19

Across TCGA patient cohorts, C4orf19 protein abundance is significantly associated with the RNA expression of many other genes, with 1,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf19-associated genes across cancer lineages are RDH10, PSMB6, and EME2. Each is linked with C4orf19 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf19-to-partner and partner-to-C4orf19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf19 versus RDH10 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf19→partner) and Y-score (partner→C4orf19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RDH10 →	+1.768	+1.142	.001	.005	3	2
BRCA	PSMB6 →	-0.770	-1.033	<.001	.003	3	2
GBM	EME2 →	+0.415	+0.676	.006	.005	3	2
LSCC	NINL →	-0.948	-1.174	<.001	.003	3	1
LSCC	DKK4 →	+1.801	+1.288	.001	.002	3	1
LSCC	ERICH1 →	-0.838	-1.129	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,209 associations by consensus.

C4orf19 vs RDH10 — LSCC

Explore this scatter interactively →