C4orf17

Across TCGA patient cohorts, C4orf17 protein abundance is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C4orf17-associated genes across cancer lineages are IFNA8, KCNJ5, and SOX9. Each is linked with C4orf17 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf17-to-partner and partner-to-C4orf17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf17 versus IFNA8 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf17→partner) and Y-score (partner→C4orf17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFNA8 →	+0.105	+0.460	.005	.006	3	1
HNSC	KCNJ5 →	+0.818	+0.584	.001	.002	3	1
HNSC	SOX9 →	+1.337	+0.394	.004	.009	3	1
HNSC	TPRKB →	+0.343	+0.439	.006	.003	3	1
HNSC	HKDC1 →	-1.337	-0.544	.003	.008	3	1
HNSC	ZNF22 →	+0.606	+0.608	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

C4orf17 vs IFNA8 — HNSC

Explore this scatter interactively →