C4orf17

Across TCGA patient cohorts, C4orf17 mutation is significantly associated with the RNA expression of many other genes, with 709 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf17-associated genes across cancer lineages are MLLT10P2, SEPTIN14P1, and NOP10. Each is linked with C4orf17 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf17-to-partner and partner-to-C4orf17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MLLT10P2 grouped by C4orf17-low versus C4orf17-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf17→partner) and Y-score (partner→C4orf17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MLLT10P2 →	+0.079	+5.054	.008	.003	3	2
LUAD	SEPTIN14P1 →	+0.156	+5.197	<.001	.003	3	2
UCEC	NOP10 →	+0.397	+2.502	.002	.009	3	2
UCEC	SFI1 →	+0.395	+3.660	<.001	.001	3	2
UCEC	NAP1L4 →	+0.348	+2.343	.001	<.001	3	2
SKCM	MIR3167 →	+0.102	+4.729	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 709 associations by consensus.

MLLT10P2 by C4orf17 expression — BRCA

Explore this box plot interactively →