C4orf17

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C4orf17 RNA expression is significantly associated with the go_rna of many other GO terms, with 211 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C4orf17-associated GO terms across cancer lineages are Choline transport, Protein targeting to vacuole involved in autophagy, and Dense core granule cytoskeletal transport. Each is linked with C4orf17 in more than 2 cancer types. Because this analysis shows association rather than direction, both C4orf17-to-partner and partner-to-C4orf17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Choline transport grouped by C4orf17-low versus C4orf17-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf17→partner) and Y-score (partner→C4orf17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaCholine transport →-0.095-0.016<.001.00533
STOMACHProtein targeting to vacuole involved in autophagy →+0.173+0.004.004.00932
PANCREASDense core granule cytoskeletal transport →-0.151-0.006<.001.00732
SOFT_TISSUERegulation of neutrophil activation →+0.138+0.018.001.00532
SOFT_TISSUE1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →-0.060-0.021.009.00632
SOFT_TISSUEPresynaptic active zone organization →-0.138-0.022<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

Choline transport by C4orf17 expression — BLOOD_Leukemia

Box plot of Choline transport in C4orf17-low vs C4orf17-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration