C4orf17

Across TCGA cell cohorts, C4orf17 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C4orf17-associated genes across cancer lineages are CCDC172, C1orf87, and OR1M1. Each is linked with C4orf17 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf17-to-partner and partner-to-C4orf17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by C4orf17-low versus C4orf17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf17→partner) and Y-score (partner→C4orf17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC172 →	+0.006	+5.415	<.001	.004	3	1
BLOOD_Lymphoma	C1orf87 →	+0.056	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR1M1 →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR9A2 →	+0.018	+5.209	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4K1 →	+0.019	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR7G3 →	+0.043	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CCDC172 by C4orf17 expression — LARGE_INTESTINE

Explore this box plot interactively →