C4BPB

Across TCGA patient cohorts, C4BPB mutation is significantly associated with the RNA expression of many other genes, with 928 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4BPB-associated genes across cancer lineages are RNA5SP367, GUF1, and CENPH. Each is linked with C4BPB in more than 1 cancer types. Because this analysis shows association rather than direction, both C4BPB-to-partner and partner-to-C4BPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP367 grouped by C4BPB-low versus C4BPB-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4BPB→partner) and Y-score (partner→C4BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP367 →	+0.547	+4.623	<.001	.001	3	2
UCEC	GUF1 →	+0.454	+2.332	.002	.003	3	2
UCEC	CENPH →	+0.715	+3.010	<.001	<.001	3	2
UCEC	SKA1 →	+0.839	+3.831	<.001	<.001	3	2
UCEC	SFXN1 →	+0.450	+2.658	.004	.005	3	2
UCEC	NIPA1 →	+0.737	+2.343	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 928 associations by consensus.

RNA5SP367 by C4BPB expression — BLCA

Explore this box plot interactively →